Vaccines are being developed to target an area of the virus that is essential for the virus to remain infectious. Therefore, a mutation in this area would result in a non-infectious virus. Remember that most mutation are detrimental to the infectivity or replication of the virus. So, it probably does not matter that the viral subtype in the US is different than the subtype in Wuhan.
We probably will have a vaccine but how well it works is undetermined.