5/4 Question

5/4 Question

by Bailey Barnard -
Number of replies: 1

Because there are very young people dying, but then there are people over 100 years old that become infected but recover just fine, do you think there is something in people's DNA or overall genetic makeup that makes the virus attack them more or makes them "weaker" against the virus? Causing them to then have worse symptoms and not be able to fight off the virus and end up dying

In reply to Bailey Barnard

Re: 5/4 Question

by Barbara Christie-Pope -

hard to know but your adaptive immune system is built around a very large group of proteins called the Major Histocompatibility Comples or the MHCs.   These proteins are what control whether or not T-cells become activated.  They therefore control activation of cytotoxic T-cells to kill viral infected cells and control T helper cells to make B cells make antibodies.  The MHCs also are unique to you and you alone.  MHCs are made from genes called the Human Leukocytic Antigens or HLAs.  We know that certain combinations of the HLA genes are linked to particular diseases.  Maybe a person susceptibility or lack of susceptibility is due to a particular set of HLAs.